Title:
血管形成または内部粥腫切除術後の再狭窄および臓器線維症を原因とする疾患の処置に有用な5β,14β-アンドロスタン誘導体
Document Type and Number:
Japanese Patent JP2010529082
Kind Code:
A
Abstract:
Compound of formula (I), wherein the symbol have the meaning reported in the text; for preparing a medicament for the prevention and/or treatment of obstructive vascular lesions following vascular surgery and for the prevention and/or treatment of diseases due to organ fibrosis.
Inventors:
Liberato Bellino
Antonio Casino
Marirena Cipollaro
Amalia Forte
Francesco Rossi
Giuseppe Bianchi
Patrizia Ferrari
Antonio Casino
Marirena Cipollaro
Amalia Forte
Francesco Rossi
Giuseppe Bianchi
Patrizia Ferrari
Application Number:
JP2010510789A
Publication Date:
August 26, 2010
Filing Date:
June 04, 2008
Export Citation:
Assignee:
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SOCIETA PER AZIONI
International Classes:
A61K31/58; A61P1/16; A61P9/00; A61P9/10; A61P17/02; A61P25/00; A61P35/00; C07J17/00
Domestic Patent References:
| JPH06157586A | 1994-06-03 | |||
| JPH07503729A | 1995-04-20 | |||
| JPH05222039A | 1993-08-31 | |||
| JPH06321945A | 1994-11-22 |
Foreign References:
| WO2006044916A2 | 2006-04-27 |
Other References:
JPN5010009209; Ｆｏｒｔｅ，Ａ． ｅｔ ａｌ．: '"ＰＳＴ ２２３８ ＴＲＥＡＴＭＥＮＴ ＡＦＦＥＣＴＳ ＧＥＮＥ ＥＸＰＲＥＳＳＩＯＮ ＩＮ ＡＲＴＥＲＩＯＴＯＭＹ-ＩＮＪＵＲＥＤ ＭＩＬＡＮ ＨＹＰＥＲＴＥＮＳＩＶＥ ＲＡＴ ＳＴＲＡＩＮ ＣＡＲ' Ｊ． Ｈｙｐｅｒｔｅｎｓｉｏｎ Ｖｏｌ．２３，Ｓｕｐｐｌ．２, 200506, Ｐ．Ｓ２４４
JPN6013007622; Ｍｏｒｉｃｅ，Ｍ．Ｃ． ｅｔ ａｌ．: '"Ａ ＲＡＮＤＯＭＩＺＥＤ ＣＯＭＰＡＲＩＳＯＮ ＯＦ Ａ ＳＩＲＯＬＩＭＵＳ-ＥＬＵＴＩＮＧ ＳＴＥＮＴ ＷＩＴＨ Ａ ＳＴＡＮＤＡＲＤ ＳＴＥＮＴ ＦＯＲ ＣＯＲＯＮＡＲＹ ＲＥＶＡＳＣＵＬＡＲＩ' Ｎｅｗ Ｅｎｇｌ． Ｊ． Ｍｅｄ． Ｖｏｌ．３４６，Ｎｏ．２３, 20020606, Ｐ．１７７３-１７８０
JPN6013007625; Ｐａｒｋ，Ｓ．Ｊ． ｅｔ ａｌ．: '"Ａ Ｐａｃｌｉｔａｘｅｌ-Ｅｌｕｔｉｎｇ Ｓｔｅｎｔ ｆｏｒ ｔｈｅ Ｐｒｅｖｅｎｔｉｏｎ ｏｆ Ｃｏｒｏｎａｒｙ Ｒｅｓｔｅｎｏｓｉｓ"' Ｎｅｗ Ｅｎｇｌ． Ｊ． Ｍｅｄ． Ｖｏｌ．３４８，Ｎｏ．１６, 20030417, Ｐ．１５３７-１５４５
JPN6013007626; 長岡昭二: '小特集／生体・医用材料と表面 『血管カテーテルの表面処理』' 表面技術 Ｖｏｌ．４６，Ｎｏ．１０, 199510, Ｐ．９１６-９１９
JPN6014004466; Ｗｉｎｎｉｃｋａ，Ｋ．，ｅｔ ａｌ．: '"ＰＳＴ ２２３８ ＡＮ ＡＮＴＩＨＹＰＥＲＴＥＮＳＩＶＥ ＣＯＭＰＯＵＮＤ ＴＨＡＴ ＡＮＴＡＧＯＮＩＺＥＳ ＴＨＥ ＥＦＦＥＣＴ ＯＦ ＥＮＤＯＧＥＮＯＵＳ ＣＡＲＤＩＡＣ ＧＬＹＣＯＳＩＤＥＳ' Ａｃｔａ Ｐｏｌ． Ｐｈａｒｍ． Ｖｏｌ．６２，Ｎｏ．１, 2005, Ｐ．７５-７９
JPN6013007622; Ｍｏｒｉｃｅ，Ｍ．Ｃ． ｅｔ ａｌ．: '"Ａ ＲＡＮＤＯＭＩＺＥＤ ＣＯＭＰＡＲＩＳＯＮ ＯＦ Ａ ＳＩＲＯＬＩＭＵＳ-ＥＬＵＴＩＮＧ ＳＴＥＮＴ ＷＩＴＨ Ａ ＳＴＡＮＤＡＲＤ ＳＴＥＮＴ ＦＯＲ ＣＯＲＯＮＡＲＹ ＲＥＶＡＳＣＵＬＡＲＩ' Ｎｅｗ Ｅｎｇｌ． Ｊ． Ｍｅｄ． Ｖｏｌ．３４６，Ｎｏ．２３, 20020606, Ｐ．１７７３-１７８０
JPN6013007625; Ｐａｒｋ，Ｓ．Ｊ． ｅｔ ａｌ．: '"Ａ Ｐａｃｌｉｔａｘｅｌ-Ｅｌｕｔｉｎｇ Ｓｔｅｎｔ ｆｏｒ ｔｈｅ Ｐｒｅｖｅｎｔｉｏｎ ｏｆ Ｃｏｒｏｎａｒｙ Ｒｅｓｔｅｎｏｓｉｓ"' Ｎｅｗ Ｅｎｇｌ． Ｊ． Ｍｅｄ． Ｖｏｌ．３４８，Ｎｏ．１６, 20030417, Ｐ．１５３７-１５４５
JPN6013007626; 長岡昭二: '小特集／生体・医用材料と表面 『血管カテーテルの表面処理』' 表面技術 Ｖｏｌ．４６，Ｎｏ．１０, 199510, Ｐ．９１６-９１９
JPN6014004466; Ｗｉｎｎｉｃｋａ，Ｋ．，ｅｔ ａｌ．: '"ＰＳＴ ２２３８ ＡＮ ＡＮＴＩＨＹＰＥＲＴＥＮＳＩＶＥ ＣＯＭＰＯＵＮＤ ＴＨＡＴ ＡＮＴＡＧＯＮＩＺＥＳ ＴＨＥ ＥＦＦＥＣＴ ＯＦ ＥＮＤＯＧＥＮＯＵＳ ＣＡＲＤＩＡＣ ＧＬＹＣＯＳＩＤＥＳ' Ａｃｔａ Ｐｏｌ． Ｐｈａｒｍ． Ｖｏｌ．６２，Ｎｏ．１, 2005, Ｐ．７５-７９
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga