5,6,7,8-TETRAHYDRO-5,8-METHANOISOQUINOLINE DERIVATIVE AND ANTIULCER AGENT

Title:

5,6,7,8-TETRAHYDRO-5,8-METHANOISOQUINOLINE DERIVATIVE AND ANTIULCER AGENT

Document Type and Number:

Japanese Patent JPS625964

Kind Code:

A

Abstract:

NEW MATERIAL:The compound of formula I (n is 0 or 1; R is heterocyclic group) and its acid addition salt.

EXAMPLE: 3-(2-Thenoylamino)-5,6,7,8-tetrahydro-5,8-methanoisoqu-inoline.

USE: Antiulcer agent.

PREPARATION: The compound of formula I can be produced by reacting the compound of formula II with the compound of formula III in a solvent such as CCl4, benzene, etc., optionally in the presence of a base (e.g. pyridine), a dehydration agent (e.g. thionyl chloride), etc.

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Inventors:

TANIDA HIROSHI
IRIE TADASHI
TSUTSUMIUCHI MASAMI

Application Number:

JP14537885A

Publication Date:

January 12, 1987

Filing Date:

July 01, 1985

Export Citation:

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Assignee:

SHIONOGI & CO

International Classes:

C07D221/22; A61K31/47; A61K31/535; A61P1/04; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; (IPC1-7): A61K31/47; C07D221/22

Attorney, Agent or Firm:

Mitsutaka Iwasaki

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