Title:
強力かつ選択的なヒストン脱アセチル化酵素阻害剤としての6-アミノニコチンアミド誘導体
Document Type and Number:
Japanese Patent JP2011520891
Kind Code:
A
Abstract:
The present invention relates to certain 6-aminonicotinamide derivatives which are capable of inhibiting histone deacetylases. The compounds of this invention are therefore useful in treating diseases associated with abnormal histone deacetylase activities. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing these compounds are also disclosed.
Inventors:
Liu, Cyan-Pin
Lee, Ji Bin
Nin, Ji-Chan
Lee, Ji Bin
Nin, Ji-Chan
Application Number:
JP2011509573A
Publication Date:
July 21, 2011
Filing Date:
May 08, 2009
Export Citation:
Assignee:
Chip Screen Biosciences LDT.
International Classes:
C07D213/82; A61K31/435; A61K31/4433; A61K31/4436; A61K31/444; A61P3/00; A61P9/00; A61P21/00; A61P25/00; A61P25/14; A61P25/18; A61P25/28; A61P35/00; A61P35/02; A61P43/00; C07D405/12; C07D409/12
Attorney, Agent or Firm:
Taro Yaguchi
Kazuya Sekiguchi
Kazuya Sekiguchi