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Title:
APJアゴニストとしての6-ヒドロキシ-5-(フェニル/ヘテロアリールスルホニル)ピリミジン-4(1H)-オン
Document Type and Number:
Japanese Patent JP6993357
Kind Code:
B2
Abstract:
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.

Inventors:
George O Tora
Heather Finley
Wen Jiang
Way men
Xiao Jun Jean
Application Number:
JP2018565285A
Publication Date:
January 13, 2022
Filing Date:
June 14, 2017
Export Citation:
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Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D239/60; A61K31/513; A61K31/5377; A61P3/10; A61P9/00; A61P9/02; A61P9/04; A61P9/10; C07D401/04; C07D401/12; C07D401/14; C07D403/12; C07D405/04; C07D405/06; C07D405/12; C07D405/14; C07D409/12; C07D413/12; C07D417/12; C07D471/04
Domestic Patent References:
JP2018535999A
JP2018538304A
JP2019509319A
JP9031061A
JP9505295A
Foreign References:
WO1996004248A1
Other References:
SCHNELL, Barbara,Journal of Heterocyclic Chemistry,2000年,37(Jul-Aug),911-919
STN International,File REGISTRY [online],Entered STN: 08 Jun 2008,2009年,CAS Registry No.1026643-26-4
Attorney, Agent or Firm:
Yamato Kento
Shinagawa
Futami Kamahira
Masahiro Suwon