Title:
ポリ(ADP-リボース)ポリメラーゼインヒビターとしての6-置換2-キノリノンおよび2-キノキサリノン
Document Type and Number:
Japanese Patent JP4806353
Kind Code:
B2
Abstract:
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, R1, R2, R3, R4 and X have defined meanings.
Inventors:
Maville, Dominique Jean-Pierre
Guilmon, Jerome Emile Giorgiuille
Ban Deyun, Jacobs Alhuons Sus Josef
Somer, Maria Victoria Francisca
Wooters, Walter Budewin Leopold
Guilmon, Jerome Emile Giorgiuille
Ban Deyun, Jacobs Alhuons Sus Josef
Somer, Maria Victoria Francisca
Wooters, Walter Budewin Leopold
Application Number:
JP2006541830A
Publication Date:
November 02, 2011
Filing Date:
November 18, 2004
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D215/22; A61K31/4704; A61K31/4709; A61K31/4725; A61K31/498; A61K45/00; A61P1/04; A61P3/10; A61P9/10; A61P17/02; A61P19/02; A61P19/10; A61P21/00; A61P21/04; A61P25/14; A61P25/16; A61P25/22; A61P25/28; A61P25/30; A61P29/00; A61P35/00; A61P37/00; A61P37/04; A61P43/00; C07D241/44; C07D401/06; C07D401/12; C07D405/06; C07D407/06; C07D409/14
Domestic Patent References:
| JPH02223579A | 1990-09-05 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office