Title:
凝固カスケードの選択阻害に有用な6員複素環式化合物
Document Type and Number:
Japanese Patent JP2005519866
Kind Code:
A
Abstract:
The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
Inventors:
South, Michael Es
Ronald Kay, Webber
Juan, Horn-Chi
Toss, Miharie Vui
Mooreman, Alan Yee
Jeffrey S. Snyder
Shorten, Jeffrey A.
Garland, Danny Jay
Rupel, Melvin El
Neumann, William Elle
Long, scott
Way fan
John the Trujillo
Parlow, John Jay
Dallin Yee, Jones
Case, blender
Hayes, Michael Jay
Ronald Kay, Webber
Juan, Horn-Chi
Toss, Miharie Vui
Mooreman, Alan Yee
Jeffrey S. Snyder
Shorten, Jeffrey A.
Garland, Danny Jay
Rupel, Melvin El
Neumann, William Elle
Long, scott
Way fan
John the Trujillo
Parlow, John Jay
Dallin Yee, Jones
Case, blender
Hayes, Michael Jay
Application Number:
JP2003532466A
Publication Date:
July 07, 2005
Filing Date:
October 03, 2002
Export Citation:
Assignee:
Pharmacia Corporation
International Classes:
C07D249/12; A61K31/451; A61K31/495; A61K31/50; A61K31/513; A61K31/53; A61K31/535; A61K45/00; A61P7/02; A61P9/10; A61P43/00; C07C257/18; C07D207/32; C07D211/56; C07D211/98; C07D213/74; C07D231/38; C07D231/48; C07D237/04; C07D239/10; C07D239/22; C07D241/04; C07D241/20; C07D249/14; C07D253/06; C07D253/075; C07D263/48; C07D265/02; C07D277/42; C07D307/22; C07D333/36; C07D401/12; C07D403/10; C07D413/12; C07D471/04; (IPC1-7): C07D211/56; A61K31/451; A61K31/495; A61K31/50; A61K31/513; A61K31/53; A61K31/535; A61K45/00; A61P7/02; A61P9/10; A61P43/00; C07D211/98; C07D213/74; C07D237/04; C07D239/10; C07D239/22; C07D241/04; C07D249/12; C07D249/14; C07D265/02
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri