Title:
凝固カスケードの選択阻害に有用な6員不飽和複素環式化合物
Document Type and Number:
Japanese Patent JP2005514332
Kind Code:
A
Abstract:
The present invention relates to compounds, and prodrugs thereof, composition and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
Inventors:
South, Michael Es
Ronald Kay, Webber
Juan, Horn-Chi
Toss, Miharie Vui
Mooreman, Alan Yee
Jeffrey S. Snyder
Shorten, Jeffrey A.
Garland, Danny Jay
Rupel, Melvin El
Neumann, William Elle
Long, scott
Way fan
John the Trujillo
Parlow, John Jay
Dallin Yee, Jones
Case, blender
Hayes, Michael Jay
Zen, Chinpin
Abbas, Zahia
Fenton, Ricky El
Castulin, Carrie El
Hayato, Rahman Kay
Sample, Kirby Earl
Schweizer, Barbara A.
Wood, Ronda Es
Suzalony, Jim
Three Manov, Ottoman Dee
Sarriers, Anita
Nicholson, Nancy S
Ronald Kay, Webber
Juan, Horn-Chi
Toss, Miharie Vui
Mooreman, Alan Yee
Jeffrey S. Snyder
Shorten, Jeffrey A.
Garland, Danny Jay
Rupel, Melvin El
Neumann, William Elle
Long, scott
Way fan
John the Trujillo
Parlow, John Jay
Dallin Yee, Jones
Case, blender
Hayes, Michael Jay
Zen, Chinpin
Abbas, Zahia
Fenton, Ricky El
Castulin, Carrie El
Hayato, Rahman Kay
Sample, Kirby Earl
Schweizer, Barbara A.
Wood, Ronda Es
Suzalony, Jim
Three Manov, Ottoman Dee
Sarriers, Anita
Nicholson, Nancy S
Application Number:
JP2003532474A
Publication Date:
May 19, 2005
Filing Date:
October 03, 2002
Export Citation:
Assignee:
Pharmacia Corporation
International Classes:
C07D239/47; A61K31/4965; A61K31/497; A61K31/513; A61K31/5377; A61K31/616; A61K45/00; A61P7/02; A61P43/00; C07C257/18; C07D207/32; C07D211/56; C07D211/98; C07D213/74; C07D231/38; C07D231/48; C07D237/04; C07D239/10; C07D239/22; C07D241/04; C07D241/20; C07D249/14; C07D253/06; C07D253/075; C07D263/48; C07D265/02; C07D277/42; C07D307/22; C07D333/36; C07D401/12; C07D403/04; C07D403/10; C07D409/12; C07D413/12; C07D471/04; (IPC1-7): C07D239/47; A61K31/4965; A61K31/497; A61K31/513; A61K31/5377; A61K31/616; A61K45/00; A61P7/02; A61P43/00; C07D241/20; C07D401/12; C07D403/04; C07D403/10; C07D409/12
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri