Title:
6*111DIHYDRODIBENZOOTHIEPINEE111ONE SSOXIDES* THEIR MANUFACTURE AND THEIR MEDICAL COMPOSITION* USE AND INTERMEDIATES USEFUL FOR THEIR PREPARATION
Document Type and Number:
Japanese Patent JPS54141793
Kind Code:
A
Abstract:
Novel 6, 11-dihydrodibenzo-[b.e.]-thiepin-11-one S-oxides, and intermediates useful in the preparation thereof, having the formulae wherein R is hydrogen, an alkyl group containing from 1 to twelve carbon atoms or a pharmaceutically acceptable salt thereof when R is hydrogen, R<1> is hydrogen, chloro or methoxy, R<2> is hydrogen or methyl, and R<3> is chloro or methoxy. The free acid or ester of compound II, or its 8-R<3> unsubstituted equivalent, can be converted to the corresponding compound I by oxidation. The compounds and compositions containing them can be used for treating inflammation or other conditions in mammals.
Inventors:
JIYATSUKU AKURERU
Application Number:
JP4856879A
Publication Date:
November 05, 1979
Filing Date:
April 21, 1979
Export Citation:
Assignee:
SYNTEX INC
International Classes:
A61K31/38; A61P25/04; A61P29/00; C07C205/57; C07D337/12; (IPC1-7): A61K31/38; C07D337/12
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