7-フェニル-1,4-ジアゼパン-誘導体、それを含有する医薬、その製造方法及びそれを製造するための出発物質

Title:

7-フェニル-1,4-ジアゼパン-誘導体、それを含有する医薬、その製造方法及びそれを製造するための出発物質

Document Type and Number:

Japanese Patent JP4380814

Kind Code:

B2

Abstract:

1-Benzoyl-4-aminoacyl-7-phenyl-1,4-diazepine derivatives (I) are new. Also new are four classes of intermediates. 1,4-Diazepine derivatives of formula (I) and their acid addition salts are new. Ph1 = phenyl substituted by R2 and R3; Ph2 = phenyl substituted by R4 and R5; Ph3 = 3-(R6)-5-(R7)-phenyl; R1 = H or alkyl; R2-R5 = H, alkyl, alkoxy, halo or CF3; or R2+R3 or R4+R5 on adjacent C = 1-2C alkylenedioxy; R6,R7 = alkyl, halo or CF3; A = (CH2)n or NH(CH2)m; n = 1-3; m = 2 or 3; and B = 1-3C alkylene chain (optionally substituted by alkyl).

More Like This:

JP2008521780	2-alkoxy-3,4,5-trihydroxyalkylamide compounds, their preparations, compositions containing them, and their use.
JP4320260	New arylamidine derivative or salt thereof
JP3347331	INDUSTRIAL APPLICABILITY: Heterocyclic metalloprotease inhibitor

Inventors:

The Muell David
Jochen Antel
Reinhard Bruchner
Dieter Ziegler
Christian Ekhut
Gerhard-Wilhelm Biellenberg
Michael peck

Application Number:

JP23712998A

Publication Date:

December 09, 2009

Filing Date:

August 24, 1998

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Solvay Pharmaceuticals GmbH

International Classes:

C07D243/08; A61K31/55; A61K31/551; A61P1/00; A61P1/08; A61P1/12; A61P29/00; A61P43/00

Domestic Patent References:

JP7242641A

Foreign References:

WO1996034864A1

Attorney, Agent or Firm:

Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Reinhard Einsel

Previous Patent: センサシステムを備える基板の製造方法

Next Patent: α−グルコシダーゼ阻害物質