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Title:
85 kDa NEISSERIAL ANTIGEN
Document Type and Number:
Japanese Patent JP2011055838
Kind Code:
A
Abstract:

To determine the antigenic components of meningitis vaccine and characterize them to enable the preparation of more preferably determined vaccine (for example, an acellular subunit vaccine), and to diverse strains of Neisseria to induce immunity.

An 85 kDa antigen from Neisseria meningitidis and Neisseria gonorrhoeae has been cloned, sequenced and expressed. The antigen is common to diverse strains, serogroups and serotypes of N. meningitidis, and also to N. gonorrhoeae, N. polysaccharia and N. lactamica. The protein sequences of N. meningitidis (serogroups A and B) and N. gonorrhoeae are highly homologous.


Inventors:
GIULIANI MARZIA MONICA
PIZZA MARIAGRAZIA
RAPPUOLI RINO
HOLST JOHAN
Application Number:
JP2010245716A
Publication Date:
March 24, 2011
Filing Date:
November 01, 2010
Export Citation:
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Assignee:
CHIRON SRL
STATENS INST FOR FOLKEHELSE
International Classes:
C12N15/09; A61K39/00; A61K39/02; A61K39/05; A61K39/08; A61K39/095; A61K39/10; A61K39/13; A61K39/145; A61K39/29; A61K39/295; A61K39/395; A61K48/00; A61P31/04; C07K14/22; C07K16/12; A61K38/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita