Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
9-BROMOMETHYLACRIDINE
Document Type and Number:
Japanese Patent JPS62238267
Kind Code:
A
Abstract:

NEW MATERIAL:9-Bromomethylacridine of formula.

USE: Useful for the analysis of carboxylic acids by using as a fluorescent and UV-absorption labeling reagent. Since the reaction product of the compound of formula and carboxylic acid has extremely high molecular extinction coefficient, carboxylic acid can be determined in high sensitivity. A high-intensity emission line of a deuterium lamp can be used as a fluorescent detector to enable high-sensitivity detection. It can be applied not only to fatty acid but also to a carboxyl-containing compound such as prostaglandin, leucotriene, etc. Applicable also for the analysis of carboxylic acid in blood and living tissue, etc.

PREPARATION: Diphenylamine is heated in acetic acid in the presence of a catalyst and the resultant 9-aminoacridine is refluxed in an organic solvent in the presence of a radical reaction initiator and a bromination agent under heating, left to cool and recrystallized to obtain the objective compound of formula.


Inventors:
MEGURO HIROMU
SUZUKI TAKEO
AKASAKA KAZUAKI
SHINDO YOSHIYUKI
TAKAHASHI HIROAKI
Application Number:
JP7825486A
Publication Date:
October 19, 1987
Filing Date:
April 07, 1986
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
TOSOH CORP
International Classes:
G01N33/50; C07D219/02; (IPC1-7): C07D219/02; G01N33/50
Other References:
CHEMICAL ABSTRACTS=1982