Title:
9-DESOXOTAXANE
Document Type and Number:
Japanese Patent JP2004002456
Kind Code:
A
Abstract:
To provide a baccatin III or 10-desacetylbaccatin III derivative or analog which has a C9 substituent other than a keto group.
This baccatin III or 10-desacetylbaccatin III derivative or analog is obtained by a method in which taxol, an taxsol analog, baccatin III or 10-desacetylbaccatin III is subjected to selective reduction so as to convert its C9 keto group into a hydroxy group corresponding thereto.
Inventors:
HOLTON ROBERT A (US)
SOMOZA CARMEN (US)
SUZUKI YUKIO (US)
SHINDO MITSURU (US)
SOMOZA CARMEN (US)
SUZUKI YUKIO (US)
SHINDO MITSURU (US)
Application Number:
JP2003272410A
Publication Date:
January 08, 2004
Filing Date:
July 09, 2003
Export Citation:
Assignee:
UNIV FLORIDA STATE (US)
International Classes:
A61K31/335; A61K31/337; A61P35/00; C07D305/14; C07D407/12; C07D409/12; C07F7/18; (IPC1-7): C07D305/14; A61K31/337; A61P35/00; C07D407/12; C07D409/12; C07F7/18
Attorney, Agent or Firm:
Aoyama Aoi
Yasuo Shibata
Yasuo Shibata