Title:
9,10-セコプレグナン誘導体及び医薬
Document Type and Number:
Japanese Patent JP5125101
Kind Code:
B2
Abstract:
The object of the present invention is to provide a novel and useful vitamin D 3 derivative which does not have much effect on the systemic calcium metabolism while retaining an excellent vitamin D 3 activity. The present invention may include a 9,10-secopregnane derivative represented by the following general formula [1] and a pharmaceutical composition containing the same as an active ingredient. In the general formula [1], Y represents (1) a single bond, (2) alkylene, (3) alkenylene or (4) phenylene; R 1 and R 2 are same or different and each represents (1) hydrogen, (2) alkyl or (3) cycloalkyl, R 1 and R 2 taken together with the carbon atom adjacent thereto may form a cycloalkyl; R 3 represents hydrogen or methyl; and Z represents (1) hydrogen, (2) hydroxy or (3) -NR 11 R 12 .
Inventors:
Hiroki Fujieda
Hironori Otsu
Shoji Anfuku
Hironori Otsu
Shoji Anfuku
Application Number:
JP2006546681A
Publication Date:
January 23, 2013
Filing Date:
December 05, 2005
Export Citation:
Assignee:
NIPPON SHINYAKU CO.,LTD.
International Classes:
C07C401/00; A61K31/59; A61P17/00; A61P17/06; A61P17/12
Domestic Patent References:
| JPH10502940A | 1998-03-17 | |||
| JPH10502940A | 1998-03-17 |
Foreign References:
| WO2001096293A1 | 2001-12-20 | |||
| WO2001096293A1 | 2001-12-20 |
Attorney, Agent or Firm:
Naoto Shimizu