Title:
AMINOACYL-tRNA SYNTHETASES FOR MODULATING INFLAMMATION
Document Type and Number:
Japanese Patent JP2015145425
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide aminoacyl-tRNA synthetases for modulating inflammation.SOLUTION: The invention provides a composition for modulating inflammation and other cellular responses comprising an aminoacyl-tRNA synthetase polypeptide including active fragments and/or variants thereof. Also provided is a method for using the composition to treat conditions that will benefit from the modulation of inflammation such as inflammatory diseases or conditions. In another embodiment, the invention provides a method for treating a disease, disorder or other condition in a subject in need of treatment by administering the composition of the invention.
Inventors:
JEFFRY DEAN WATKINS
ALAIN P VASSEROT
LESLLE ANN GREENE
RYAN ANDREW ADAMS
KYLE P CHIANG
ZHANG WEI
KRISTI HELEN PIEHL
HONG FEI
ALINA HE
ALAIN P VASSEROT
LESLLE ANN GREENE
RYAN ANDREW ADAMS
KYLE P CHIANG
ZHANG WEI
KRISTI HELEN PIEHL
HONG FEI
ALINA HE
Application Number:
JP2015098145A
Publication Date:
August 13, 2015
Filing Date:
May 13, 2015
Export Citation:
Assignee:
ATYR PHARMA INC
International Classes:
A61K38/45; A61K31/7088; A61K35/76; A61K48/00; A61P3/00; A61P3/10; A61P9/10; A61P11/00; A61P17/00; A61P19/00; A61P19/02; A61P25/00; A61P29/00; A61P31/00; A61P35/00; A61P35/02; A61P37/00; A61P37/04; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/00; C12N15/09
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto