Title:
ASC as a marker of a chronic obstructive pulmonary disease (COPD)
Document Type and Number:
Japanese Patent JP5976695
Kind Code:
B2
Abstract:
An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an individual, by measuring the protein ASC in said sample in vitro.
Inventors:
Andres, Herbert
Carl, Johann
Reed Ringer, Yulia
Carl, Johann
Reed Ringer, Yulia
Application Number:
JP2013558370A
Publication Date:
August 24, 2016
Filing Date:
March 07, 2012
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
G01N33/543; G01N33/53
Foreign References:
| WO2006105252A2 | ||||
| US20100150938 | ||||
| US20030224438 | ||||
| WO2007077042A1 |
Other References:
MIKIO TOMIDA,SERUM LEVELS OF NICOTINAMIDE N-METHYLTRANSFERASE IN PATIENTS WITH LUNG CANCER,JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,ドイツ,SPRINGER,2009年 2月26日,V135 N9,P1223-1229
KIM Ho Cheol et al.,Expression and Functional Significance of Nicotinamide N-methyl Transferase in Skeletal Muscles of Patients with Chronic Obstructive Pulmonary Disease,Am J Respir Crit Care Med,2010年,Vol.181 No.8,Page.797-805
Greenbaum D et al.,Comparing protein abundance and mRNA expression levels on a genomic scale,Genome Biol,2003年,Vol.4 No.9,Page.117.1-117.8
GYGI S P et al.,Correlation between Protein and mRNA Abundance in Yeast,Mol Cell Biol,1999年,Vol.19 No.3,Page.1720-1730
Kharitonov SA et al.,Effects of corticosteroids on noninvasive biomarkers of inflammation in asthma and chronic obstructive pulmonary disease,Proc Am Thorac Soc,2004年,Vol.1 No.3,Page.191-199
Max Tze-Han Huang, Debra J. Taxman, Elizabeth A. Holley-Guthrine, et al.,Critical Role of Apoptotic Speck Protein Containing a Caspase Recruitment Domain (ASC) and NLRP3 in Causing Necrosis and ASC Speck Formation Induced by Porphyromonas gingivalis in Human Cells,The Journal of Immunology,米国,2009年 2月15日,Vol.182 No.4,Page2395-2404
KIM Ho Cheol et al.,Expression and Functional Significance of Nicotinamide N-methyl Transferase in Skeletal Muscles of Patients with Chronic Obstructive Pulmonary Disease,Am J Respir Crit Care Med,2010年,Vol.181 No.8,Page.797-805
Greenbaum D et al.,Comparing protein abundance and mRNA expression levels on a genomic scale,Genome Biol,2003年,Vol.4 No.9,Page.117.1-117.8
GYGI S P et al.,Correlation between Protein and mRNA Abundance in Yeast,Mol Cell Biol,1999年,Vol.19 No.3,Page.1720-1730
Kharitonov SA et al.,Effects of corticosteroids on noninvasive biomarkers of inflammation in asthma and chronic obstructive pulmonary disease,Proc Am Thorac Soc,2004年,Vol.1 No.3,Page.191-199
Max Tze-Han Huang, Debra J. Taxman, Elizabeth A. Holley-Guthrine, et al.,Critical Role of Apoptotic Speck Protein Containing a Caspase Recruitment Domain (ASC) and NLRP3 in Causing Necrosis and ASC Speck Formation Induced by Porphyromonas gingivalis in Human Cells,The Journal of Immunology,米国,2009年 2月15日,Vol.182 No.4,Page2395-2404
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto