Title:
アシルコエンザイムAを用いるアシル基転移酵素反応方法
Document Type and Number:
Japanese Patent JP4353484
Kind Code:
B2
Abstract:
The present invention relates to a method for acyltransferase reaction in which an acyl group of acyl coenzyme A is transferred to an acyl group receptor characterized in that the reaction is carried out by production and/or reproduction of acyl coenzyme A from coenzyme A in a reaction system by a chemical thioester exchange reaction with acylthioester. The present invention, wherein expensive acyl CoA is reproduced nonenzymatically in a reaction system, enables to continuously carry out acyltransferase reaction only by putting a small amount of acyl CoA with a donor and a receptor of an acyl group into a system. Accordingly, the method of the present invention can be applied to an industrial production method of various kinds of compounds including useful biological molecules and synthesis of polymers such as polyester.
More Like This:
Inventors:
Motoaki Kamike
Harumi Kamaike
Hiroshi Aoki
Tomoki Erada
Kenji Tajima
Harumi Kamaike
Hiroshi Aoki
Tomoki Erada
Kenji Tajima
Application Number:
JP2005508108A
Publication Date:
October 28, 2009
Filing Date:
January 21, 2004
Export Citation:
Assignee:
SHOWA DENKO K.K.
International Classes:
C12P7/62; C12N9/10; C12N15/54; C12P13/00; C12P13/02; C12N15/09
Foreign References:
| WO2002008428A1 | ||||
| WO1998039453A1 |
Other References:
FEMS Microbiol.Lett.,Vol.168,No.2(1998)p.319-324
Arch.Biochem.Biophys.,Vol.394,No.1(2001)p.87-98
J.Biol.Chem.,Vol.276,No.21(2001)p.18249-18256
高分子学会予稿集,Vol.52,No.14(2003.Sep.)p.4216-4217
高分子学会予稿集,Vol.52,No.5(2003.May)p.996
Appl.Microbiol.Biotechnol.,Vol.53,No.5(2000)p.545-552
Biochemistry,Vol.40,No.4(2001)p.1011-1019
Appl.Microbiol.Biotechnol.,Vol.56,No.1-2(2001)p.131-136
J.Org.Chem.,Vol.56,No.11(1991)p.3752-3755
Proc.Natl.Acad.Sci.USA.,Vol.91,No.17(1994)p.7899-7902
FEMS Microbiol.Lett.,Vol.182,No.1(2000)p.111-117
Biochim.Biophys.Acta,Vol.877,No.3(1986)p.334-341
Arch.Biochem.Biophys.,Vol.394,No.1(2001)p.87-98
J.Biol.Chem.,Vol.276,No.21(2001)p.18249-18256
高分子学会予稿集,Vol.52,No.14(2003.Sep.)p.4216-4217
高分子学会予稿集,Vol.52,No.5(2003.May)p.996
Appl.Microbiol.Biotechnol.,Vol.53,No.5(2000)p.545-552
Biochemistry,Vol.40,No.4(2001)p.1011-1019
Appl.Microbiol.Biotechnol.,Vol.56,No.1-2(2001)p.131-136
J.Org.Chem.,Vol.56,No.11(1991)p.3752-3755
Proc.Natl.Acad.Sci.USA.,Vol.91,No.17(1994)p.7899-7902
FEMS Microbiol.Lett.,Vol.182,No.1(2000)p.111-117
Biochim.Biophys.Acta,Vol.877,No.3(1986)p.334-341
Attorney, Agent or Firm:
Kunihisa Landlord
Atsushi Hayashi
Atsushi Hayashi