Title:
「CEST」用途のための、磁気共鳴シフト試薬と交換性プロトンを含有する基質との付加物
Document Type and Number:
Japanese Patent JP4891763
Kind Code:
B2
Abstract:
Disclosed are CEST paramagnetic agents comprising a substrate (SH) containing mobile protons bonded to a paramagnetic chelate (SR) containing a metal selected from iron (II) (high-spin configuration), iron (III), cobalt (II), rhodium (II), copper (II), nickel (II), cerium (III), praseodymium (III), neodymium (III), dysprosium (III), erbium (III), terbium (III), holmium (III), thulium (III), ytterbium (III) and europium (III).
Inventors:
Aime, Silvio
Tereno, Enzo
Delli Castelli, Daniela
Gioventana, Giovanni Battista
Tereno, Enzo
Delli Castelli, Daniela
Gioventana, Giovanni Battista
Application Number:
JP2006505027A
Publication Date:
March 07, 2012
Filing Date:
April 06, 2004
Export Citation:
Assignee:
BRACCO IMAGING S.p.A.
International Classes:
A61K49/00; A61K47/34; A61K47/36; A61K47/42; A61K47/48; A61K49/08; A61K49/10
Domestic Patent References:
| JPH0597712A | 1993-04-20 | |||
| JP2002512942A | 2002-05-08 |
Foreign References:
| WO2003013617A2 | 2003-02-20 | |||
| EP1106186A2 | 2001-06-13 | |||
| WO2002040060A2 | 2002-05-23 | |||
| WO2002043775A2 | 2002-06-06 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda