Title:
シトクロムP450レダクターゼ活性の調整
Document Type and Number:
Japanese Patent JP2005532807
Kind Code:
A
Abstract:
A conditional hepatic cytochrome P450 reductase specific null homozygous non-human transgenic animal having depleted or ablated cytochrome P450 reductase (CPR) expression and other phenotypic characteristics.
Inventors:
Charles Roland, Wolf
Colin Jay, Henderson
Colin Jay, Henderson
Application Number:
JP2004520831A
Publication Date:
November 04, 2005
Filing Date:
July 09, 2003
Export Citation:
Assignee:
Imperial Cancer Research Technology Limited
International Classes:
A01K67/027; C12N9/02; C12N15/09; C12N15/85; C12Q1/26; G01N33/15; G01N33/50; (IPC1-7): A01K67/027; C12N15/09; C12Q1/26; G01N33/15; G01N33/50
Domestic Patent References:
| JPH11513241A | 1999-11-16 | |||
| JP2001054337A | 2001-02-27 | |||
| JP2001519163A | 2001-10-23 |
Foreign References:
| WO2000034506A2 | 2000-06-15 | |||
| WO2001094598A2 | 2001-12-13 |
Other References:
JPN6009044292, Ｊ Ｂｉｏｌ Ｃｈｅｍ．（２００２ Ｆｅｂ），Ｖｏｌ．２７７，Ｎｏ．８，ｐ．６５３６−６５４１
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JPN6010019023, Ｂｉｏｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ Ｔｒａｎｓａｃｔｉｏｎｓ（２０００），Ｖｏｌ．２８，Ｎｏ．２，ｐ．４２−４６
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JPN6010019023, Ｂｉｏｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ Ｔｒａｎｓａｃｔｉｏｎｓ（２０００），Ｖｏｌ．２８，Ｎｏ．２，ｐ．４２−４６
JPN6010019026, Ｄｒｕｇ Ｍｅｔａｂｏｌｉｓｍ Ｒｅｖｉｅｗｓ（１９９９），Ｖｏｌ．３１，Ｎｏ．２，ｐ．４３７−４４７
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Arihara Koichi
Matsushima Tetsuo