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Title:
アジュバント混合製剤
Document Type and Number:
Japanese Patent JP4974414
Kind Code:
B2
Abstract:
The use of 3-O-deacylated monophosphoryl lipid A or monophosphoryl lipid A and derivatives and analogs thereof, in combination with a cytokine or lymphokine such as granulocyte macrophage colony stimulating factor or interleukin-12 is useful as an adjuvant combination in an antigenic composition to enhance the immune response in a vertebrate host to a selected antigen.

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Inventors:
Michael Hagen
Application Number:
JP2000617916A
Publication Date:
July 11, 2012
Filing Date:
May 12, 2000
Export Citation:
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Assignee:
Wyeth Holdings Corporation
International Classes:
A61K9/107; A61K38/00; A61K39/39; A61K39/00; A61K39/02; A61K39/095; A61K39/12; A61K39/155; A61K39/21; A61K39/35; A61P25/28; A61P31/04; A61P31/12; A61P31/16; A61P31/20; A61P35/00; A61P37/04; C07K14/52; C07K14/535; C07K14/54; C07K19/00
Domestic Patent References:
JP9506887A
JP3502881A
JP8510749A
Foreign References:
WO1998057659A11998-12-23
WO1998056414A11998-12-17
WO1999010375A21999-03-04
Attorney, Agent or Firm:
Patent business corporation Odashima patent office



 
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