ADJUVANT, AND VACCINE FOR FISHERY

Japanese Patent JP2013184922

A

To provide a technology capable of controlling an infectious disease caused by intracellular parasitic pathogen of fishes by a highly effective vaccine.

An adjuvant for an inactivated vaccine against intracellular parasitic pathogen of fishes, including 1-type interferon or interferon-γ is provided. The adjuvant is especially useful for enhancement of vaccine effect of an inactivated vaccine against Edwardsiella tarda of a flatfish. Further, a vaccine against intracellular parasitic pathogen is also provided, which is obtained by combining inactivated intracellular parasitic pathogen of fishes or a non-infectious antigen of pathogen having vaccine activity, with 1-type interferon or interferon-γ.

TAKANO MICHIKAZU
MATSUYAMA TOMOMASA
SAKAI TAKAMITSU
NAKAI CHISA
FUJIWARA ATSUSHI

JP2012050959A

September 19, 2013

March 07, 2012

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FISHERIES RESEARCH AGENCY

A61K39/39; A01K61/00; A01K61/13; A61K39/07; A61P31/04; C12N15/09

JP2007238505A	2007-09-20
JP2008050300A	2008-03-06

JPN6015043028; 難波　亜紀　外６名: 'ギンブナの＜ｉ＞Ｅｄｗａｒｄｓｉｅｌｌａ　ｔａｒｄａ＜／ｉ＞人為感染に対するＩＦＮgammaの投与効果' 平成２３年度日本水産学会春季大会（日本農学大会水産部会）講演要旨集 , 20110327, ｐ．１５８
JPN6015043030; 村上　浩紀　外２名: '魚類リンパ球の不死化と魚インターフェロン遺伝子' 魚病研究 第３０巻，第２号, 199506, ｐ．１７５-１８０
JPN6015043031; Ｏｈｔａ　Ｔ，　ｅｔ　ａｌ．: 'Ａｎｔｉ-ｖｉｒａｌ　ｅｆｆｅｃｔｓ　ｏｆ　ｉｎｔｅｒｆｅｒｏｎ　ａｄｍｉｎｉｓｔｒａｔｉｏｎ　ｏｎ　ｓｅｖｅｎｂａｎｄ　ｇｒｏｕｐｅｒ，　Ｅｐｉｎｅｐｈｅｌｕｓ　ｓｅｐｔｅｍｆａｓｃｉａｔｕｓ' Ｆｉｓｈ　＆　Ｓｈｅｌｌｆｉｓｈ　Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．３０，　Ｎｏ．４-５, 2011, ｐ．１０６４-１０７１
JPN6015043033; 中西　照幸: '魚類ワクチン開発の現状と展望' 水産増殖 第４６巻，第３号, 1998, ｐ．４６１-４６８

Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki
Junzo Koike
Hirofumi Toma

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