Title:
AGENT FOR INHIBITING METASTASIS AND INFILTRATION OF CANCER CELL BY INHIBITION OF EXPRESSION OF CRK ADAPTOR MOLECULE
Document Type and Number:
Japanese Patent JP2006166727
Kind Code:
A
Abstract:
To provide a cancer remedy for preventing the infiltration and metastasis of cancer.
This agent for preventing the infiltration and metastasis of human cancer contains as an active ingredient a recombinant retrovirus which expresses a c-Crk double-stranded siRNA (small interference RNA) containing a nucleotide chain selected from the group consisting of GCCUGAAGAGCAGUGGUGG(sequence No. 1), AAGCCUGAAGAGCAGUGGUGG(sequence No. 2), GCCUGAAGAGCAGUGGUGGAAG(sequence No. 3) and AAGCCUGAAGAGCAGUGGUGGAAG(sequence No. 4) and a nucleotide chain complementary thereto.
Inventors:
HANABUSA HIDESABURO
AKAGI TAKESHI
IWAHARA HISANORI
AKAGI TAKESHI
IWAHARA HISANORI
Application Number:
JP2004360111A
Publication Date:
June 29, 2006
Filing Date:
December 13, 2004
Export Citation:
Assignee:
OSAKA BIOSCIENCE INST
International Classes:
C12N15/09; A61K35/76; A61P35/04; C12N7/00; C12N7/01; C12N15/113; C12R1/93
Attorney, Agent or Firm:
Kyousei Tamura
Toshio Ueda
Nagatoshi Shinagawa
Toshio Ueda
Nagatoshi Shinagawa