PURPOSE: To obtain the subject implantation-inhibitory agent effective for preventing infectious diseases caused by a pathogenic microorganism, especially pathogenic Escherichia coli or dental caries bacteria, comprising lactoferrin or a protease decomposition product thereof as an active ingredient.
CONSTITUTION: An implantation-inhibitory agent comprising lactoferrin isolated from secreted solution such as cow's milk, sheep's milk, goat's milk or human milk or a decomposition product thereof with protease prepared by limited decomposition so as not to make lactoferrin into extremely low molecular weight. The combined use of the agent with k-casein or a decomposition product thereof with protease provides wide implantation preventing effects on many strains. Dental carries, skin inframmation such as pimple and food intoxification can be prevented before their onsets by adding an effective mount of the active ingredient to food and drink, drug and cosmetic.
DOSEMARI SHUNICHI
ISODA HIROKO
JPS63284133A | 1988-11-21 |