Title:
再現性良好な凝集イムノアッセイ法及び試薬
Document Type and Number:
Japanese Patent JP4733335
Kind Code:
B2
Abstract:
The present invention provides an agglutination immunoassay, wherein the agglutination of insoluble carrier particles such as latex are stabilized and uniformized to give good reproducibility, and a reagent therefor. In the agglutination immunoassay which comprises allowing an antigenic substance in a sample to bind to insoluble carrier particles carrying substantially neither antigens nor antibodies thereon, and allowing an antibody or an antibody complex which reacts specifically to the antigenic substance to bind to the antigenic substance to give a selective agglutination of the insoluble carrier particles, a homopolymer prepared by polymerization of a monomer such as 2-methacryloyloxyethyl phosphorylcholine having a phosphorylcholine group and a vinyl group, or a copolymer prepared by polymerization of a monomer having a phosphorylcholine group and a vinyl group, with a monomer having a vinyl group such as n-butyl methacrylate is used.
Inventors:
Shigenobu Kayoko
Kenshiro Suto
Sakaki Shujiro
Kenshiro Suto
Sakaki Shujiro
Application Number:
JP2002523622A
Publication Date:
July 27, 2011
Filing Date:
August 28, 2001
Export Citation:
Assignee:
Kyowa Medex Co., Ltd.
NOF CORPORATION
TFB Co., Ltd.
NOF CORPORATION
TFB Co., Ltd.
International Classes:
G01N33/543; C08F220/60; C08F230/02; G01N33/53; G01N33/545; G01N33/577; G01N33/72
Domestic Patent References:
| JPS62218865A | 1987-09-26 | |||
| JPS61274261A | 1986-12-04 | |||
| JPH08101196A | 1996-04-16 | |||
| JPS52123295A | 1977-10-17 | |||
| JPS5426327A | 1979-02-27 | |||
| JPS61159166A | 1986-07-18 | |||
| JPS62259063A | 1987-11-11 |
Attorney, Agent or Firm:
Masaki Hirota