To provide an α-glucosidase inhibitor that can effectively inhibit the activity of α-glucosidase and is ingested as a food because of its high safety for human bodies.
Vegetable or animal protein is hydrolyzed, purified with ion- exchange resin and subjected to gel filtration with molecular sieve and the resultant protein with a molecular weight of 200-1,000 shows the α-glucosidase inhibitory activity. This protein still retains its α-glucosidase inhibitory activity even after it is isolated or remains in a mixture. The peptides which are isolated and have still high inhibitory activity are the following proteins of 5 kinds having amino acid sequences of formulas (1)-(5): formula (1): Ile-Ile-Ser-Ile-Gly, formula (2): Ile-Ile-Ser-Ile-Gly-Arg, formula (3): Val-Phe-Ile-Lys-Ala-Ala, formula (4): Val-Phe-Ile-Lys-Ala-Ala-Ala, and formula (5): Val-Phe-Ile-Lys-Ala.
| JP2005245285 | METHOD FOR PRODUCING DEGRADED MATERIAL OF COLLAGEN |
| WO/2002/089606 | ZINC-CONTAINING FOODS |
| JP2011120585 | TEA-BASED PRODUCT |
DOGE TORU
OBARA MITSUO
SHIOMI TOKUO
ONODERA SHUICHI
