Title:
ALLELE FOR OBSERVING GENE EXPRESSION RELEVANT TO TUMOR
Document Type and Number:
Japanese Patent JP3897086
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To elucidate the mechanism of action of an antitumor agent, or the like.
SOLUTION: Both of a DNA fragment complementarily bining with a DNA molecule descriptive of the gene of the pivot of the genesis, invasion or metastasis of human tumor or complementary DNA (cDNA) molecule for mRNA molecule and a DNA fragment complementarily bining with a DNA molecule descriptive of the gene of the pivot of drum metabolism or a complementary DNA (cDNA) molecule for mRNA are immobilized on a solid surface, and the difference between the melting temperature of the above immobilized DNA fragments and the hybridization temperature is kept below 30°C. As a result, a DNA allele for elucidating the mechanism of action of the antitumor agent, or the like is obtained with high precision.
Inventors:
Hiroyuki Tomita
Toshiro Saito
Masatoshi Narahara
Koichi Kato
Toshiro Saito
Masatoshi Narahara
Koichi Kato
Application Number:
JP2000255737A
Publication Date:
March 22, 2007
Filing Date:
August 22, 2000
Export Citation:
Assignee:
株式会社日立製作所
International Classes:
C12N15/09; G01N33/53; C12M1/00; C12Q1/68; G01N33/566; G01N33/574; G01N35/02; G01N37/00; (IPC1-7): C12N15/09; C12M1/00; C12Q1/68; G01N33/53; G01N33/566; G01N33/574; G01N35/02; G01N37/00
Domestic Patent References:
| JP2003505022A |
Foreign References:
| WO1999033982A1 |
Attorney, Agent or Firm:
Yusuke Hiraki
Yasuo Sakuta
Yasuo Sakuta
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