Title:
ALPHAABENZILIDINE CYCLOALKANONE AND CORRESPONDING ALCOHOL
Document Type and Number:
Japanese Patent JPS5498747
Kind Code:
A
Abstract:
Hydroxy- and oxo-substituted alpha -benzylidenylcycloalkanes having the formula: Z1, Z2 and Z3 each denotes a methoxy group or Z1 or Z2 and Z3 together denote a methylenedioxy group, and Z3 is a hydrogen atom or chlorine atom, one of the symbols R1 and R2 denotes a hydrogen atom and the other denotes a hydroxyl group or, together the two denote an oxygen atom; R3 denotes a hydrogen atom or a methyl group; R4 denotes a hydrogen atom, a methyl group or an aminomethyl group, the amino group being a dimethylamino, diethylamino, morpholino, 4-methyl-piperazino or piperidino radical; or R3 and R4 together denote a piperonylidene group; R5 denotes a hydrogen atom or a methyl group, and A forms, with the carbon atoms to which it is attached, a cyclopentane, cyclohexane, indane, tetrahydronaphthalene, perhydronaphthalene or piperidine structure and the pharmaceutically acceptable addition salts of the compounds containing an amino group. The compounds have pharmacological activity on the central nervous system.
Inventors:
FURANSOWA BARE
Application Number:
JP9356378A
Publication Date:
August 03, 1979
Filing Date:
August 02, 1978
Export Citation:
Assignee:
UNICLER
International Classes:
C07D295/10; A61K31/075; A61K31/085; A61K31/12; A61K31/357; A61K31/36; A61K31/445; A61P25/00; A61P25/08; A61P25/20; A61P25/24; A61P25/26; C07C41/00; C07C43/23; C07C45/00; C07C49/587; C07C49/753; C07C67/00; C07C213/00; C07C217/74; C07D295/08; C07D317/54; C07D317/58; (IPC1-7): A61K31/075; A61K31/12; A61K31/13; C07C41/00; C07C43/20; C07C45/00; C07C49/45; C07C93/14; C07D295/04; C07D317/48