Title:
ＲＮＡおよび／またはＤＮＡ含有ウイルスにより引き起こされる疾患と合併症の治療および予防のための薬剤としてのアミド化合物、およびその使用
Document Type and Number:
Japanese Patent JP6915911
Kind Code:
B2
Abstract:
The present invention relates to medicine and is concerned with a compound of formula (a) below or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of the compound of formula (a) or a pharmaceutically acceptable salt thereof; and kits comprising the pharmaceutical composition comprising an effective amount of the compound of formula (a) or a pharmaceutically acceptable salt thereof, pharmaceutically acceptable carriers and excipients, and instructions for use thereof; for use in preventing or treating diseases caused by RNA- and DNA-containing viruses, and concomitant diseases. The invention addresses the object of providing a compound for use in the prevention or treatment of diseases or complications of infectious diseases, whereby the diseases or infectious diseases are caused by an RNA-containing virus belonging to the Enterovirus, Metapneumovirus, Pneumovirus, Respirovirus, or Alfa-coronavirus genus, and/or by a DNA-containing virus belonging to the Adenoviridae and/or Herpesviridae family; for use in the prevention or treatment of asthma exacerbation, chronic obstructive pulmonary disease, mucoviscidosis, conjunctivitis, gastroenteritis, hepatitis, myocarditis; and for use in the prevention or treatment of rhinorrhea, acute and infectious rhinitis, pharyngitis, nasopharyngitis, tonsillitis, laryngitis, laryngotracheitis, laryngotracheobronchitis, bronchitis, bronchiolitis, pneumonia, or airway obstructive syndrome.
Inventors:
Nebolycin, Vladimir Evgenievich
Kromova, Tatiana Alexandrovna
Kromova, Tatiana Alexandrovna
Application Number:
JP2020002612A
Publication Date:
August 04, 2021
Filing Date:
January 10, 2020
Export Citation:
Assignee:
Obsevtsvos Ogranike Noi Otovetsvenostu "Fermenter Prizes"
International Classes:
C07D207/09; A61K9/20; A61K31/16; A61K31/17; A61K31/341; A61K31/381; A61K31/40; A61K31/4045; A61K31/41; A61K31/415; A61K31/417; A61K31/4178; A61K31/4192; A61K31/4196; A61K31/42; A61K31/4245; A61K31/426; A61K31/427; A61K31/428; A61K31/433; A61K31/435; A61K31/437; A61K31/439; A61K31/4402; A61K31/4409; A61K31/4439; A61K31/4458; A61K31/4462; A61K31/45; A61K31/454; A61K31/495; A61K31/4965; A61K31/50; A61K31/505; A61K31/519; A61K31/5375; A61K31/55; A61P1/00; A61P1/16; A61P9/00; A61P11/00; A61P11/06; A61P27/02; A61P29/00; A61P31/12; A61P31/14; A61P31/22; C07C237/10; C07C279/14; C07D207/28; C07D207/335; C07D209/14; C07D211/26; C07D213/40; C07D213/61; C07D213/64; C07D213/74; C07D231/12; C07D231/40; C07D233/24; C07D233/64; C07D233/66; C07D235/14; C07D237/08; C07D239/26; C07D241/04; C07D241/12; C07D249/04; C07D249/08; C07D249/18; C07D257/04; C07D261/08; C07D261/10; C07D261/12; C07D263/32; C07D265/30; C07D271/08; C07D275/02; C07D277/28; C07D277/64; C07D285/10; C07D285/14; C07D307/52; C07D307/54; C07D333/20; C07D401/04; C07D403/12; C07D417/12; C07D453/02; C07D471/04; C07D487/04; C07D513/04
Domestic Patent References:
| JP2013060432A |
Foreign References:
| US20110224213 | ||||
| EP1020179A1 |
Other References:
Corts, G. J. B. et al.,Tetracyclic γ-carboline derivatives. Synthesis of 2,8-substituted octahydroindolo [3,2-a] quinolizi,Recueil des Travaux Chimiques des Pays-Bas,1966年,85(7),744-52
REGISTRY[online],検索日2019年8月21日,CAS登録番号1481826-55-4等
REGISTRY[online],検索日2019年8月21日,CAS登録番号1481826-55-4等
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kaoru Takahashi
Nao Oda
Akiyo Iwahori
Kaoru Takahashi