Title:
アミド誘導体
Document Type and Number:
Japanese Patent JP4619545
Kind Code:
B2
Abstract:
The invention concerns amide derivatives of Formula (Ia) wherein X is -NHCO- or -CONH-; m is 0-3; R1 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; n is 0-2; R2 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino and carboxy; R3 is hydrogen, halogeno, (1-6C)alkyl or (1-6C)alkoxy; q is 0-4; and Q is a group such as aryl, aryloxy, aryl-(1-6C)alkoxy, arylamino and N-(1-6C)alkyl-arylamino; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
Inventors:
Brown, Diag Sutherland
Application Number:
JP2000605582A
Publication Date:
January 26, 2011
Filing Date:
March 13, 2000
Export Citation:
Assignee:
AstraZeneca Activrag
International Classes:
C07D239/91; A61K31/517; A61K31/5377; A61K31/55; A61K31/551; A61P1/00; A61P9/10; A61P11/06; A61P17/00; A61P19/02; A61P19/10; A61P25/00; A61P29/00; A61P31/04; A61P31/18; A61P43/00; C07D239/96; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D413/12; C07D417/12; C07D203/00; C07D207/00; C07D213/00; C07D239/70; C07D241/02; C07D243/00; C07D307/00
Other References:
KOZHEVNIKOV,Y.V.,Synthesis of nitro and amino derivatives of 2-methyl-3-aryl-4-quinazolone,Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya,1971年,Vol.14, No.11,p.1685-9
Attorney, Agent or Firm:
Kazuo Shamoto
Shosuke Imai
Tadashi Masui
Yasushi Kobayashi
Hiroyuki Tomita
Shosuke Imai
Tadashi Masui
Yasushi Kobayashi
Hiroyuki Tomita