Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
AMINE DERIVATIVE COMPOUND FOR TREATMENT OF EYE DISEASES AND DISORDERS
Document Type and Number:
Japanese Patent JP2015091842
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide an amine derivative useful for treatment of eye diseases and disorders, e.g. age-related macular degeneration and Stargardt Disease, and a pharmaceutical composition using the same.SOLUTION: There are provided an amine derivative represented by the formula (A) and a pharmaceutical composition using the same. In the formula (A), Z is a bond, an alkylene group which may be substituted by a hydroxyl group, an oxo group or the like, -X-alkylene group or the like; X is -O-, -S-, -S(=O)-, -NH- or the like; G is an alkyl group which may be substituted by a hydroxyl group, a phenyl group or the like; R, R, R, and Rare H, an alkyl group or the like; each Ris a halogen atom, an alkoxy group, an alkyl group, a fluoroalkyl group or the like; and n is an integer of 0 to 4.

Inventors:
SCOTT IAN L
VLADIMIR A KUKSA
ORME MARK W
HONG FENG
LITTLE THOMAS L JR
KUBOTA MAKOTO
Application Number:
JP2014261934A
Publication Date:
May 14, 2015
Filing Date:
December 25, 2014
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
ACUCELA INC
International Classes:
C07C211/27; A61K31/135; A61K31/137; A61K31/138; A61K31/155; A61K31/165; A61K31/351; A61K31/381; A61K31/382; A61K31/4406; A61K35/12; A61P9/10; A61P27/02; C07C211/30; C07C215/28; C07C215/30; C07C215/34; C07C215/38; C07C215/42; C07C215/68; C07C217/10; C07C217/16; C07C217/20; C07C217/48; C07C217/72; C07C219/22; C07C225/16; C07C233/18; C07C233/65; C07C235/34; C07C237/20; C07C237/30; C07C237/38; C07C237/40; C07C279/08; C07C317/30; C07C317/32; C07C323/30; C07C323/32; C07D213/30; C07D309/06; C07D333/16; C07D335/02
Domestic Patent References:
JPS53149936A1978-12-27
Foreign References:
WO2001058487A12001-08-16
WO2001058487A12001-08-16
Attorney, Agent or Firm:
Asamura patent office