アミノシクロペンチルピリドピラジノン系ケモカイン受容体活性調節剤

Japanese Patent JP2007519734

A

Compounds of Formula I and Formula II (wherein A, E, j, k, m, n, R¹, R², R³, R⁴, R⁵, R⁶, R⁷, R⁸, R⁹, R¹⁰, R¹⁵, R¹⁶, R¹⁷, R¹⁸, R¹⁹, R²⁴, R²⁵, R²⁶, R²⁷, R²⁸, R²⁹, R³⁰, R³¹, R³², R³³, R³⁴, X, Y and Z are as defined herein) which are modulators of chemokine receptor activity and are useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which chemokine receptors are involved.

WO/2015/046988	HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME
JP2009523170	Condensed Triazole Tachykinin Receptor Andanist
WO/2000/001696	3-ALKYLPYRROLO[3,2-$i(c)]QUINOLINE DERIVATIVES

Bootla, gabor
Gia Dean, Deodea Shin
Kosanda Raman, Siyan Karan
Matsukos, Malcolm
Mills, Thunder Gee
Yang, Lifou

JP2006551434A

July 19, 2007

January 26, 2005

Click for automatic bibliography generation  

MERCK & COMPANY INCOPORATED

C07D471/04; A01N43/58; A01N43/60; A01N43/64; A01N43/66; A61K31/4375; A61K31/495; A61K31/50; A61K31/53; A61P1/02; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P17/00; A61P19/02; A61P21/00; A61P25/00; A61P29/00; A61P31/12; A61P31/18; A61P33/00; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D241/36; C07D253/08; C07D471/00; C07D487/00

Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura

Previous Patent: アンパカインにより誘導されるシナプス応答促通のコリンエステラーゼ阻�...

Next Patent: ＨＩＶインテグラーゼ阻害剤として有用であるＮ−ベンジル−３，４−ジ�...