Title:
ムスカリンアゴニストとしてのアミノ置換ジアリール[a,d]シクロヘプテン類似体および精神神経疾患の治療方法
Document Type and Number:
Japanese Patent JP2007534656
Kind Code:
A
Abstract:
Disclosed herein are analogs of clozapine and pharmaceutically acceptable salts, esters, amides, or prodrugs thereof; methods of synthesizing the analogs; and methods of using the analogs for treating neuorpsychiatric disorders. In some embodiments, the analogs are amino substituted diaryl[a,d]cycloheptenes.
Inventors:
OK, Fredrick
Olson, Roger
Allson, Jorgen
Olson, Roger
Allson, Jorgen
Application Number:
JP2006547344A
Publication Date:
November 29, 2007
Filing Date:
December 21, 2004
Export Citation:
Assignee:
Acadia Pharmaceuticals, Inc.
International Classes:
C07D223/20; A61K31/55; A61K31/551; A61K31/553; A61K31/554; A61K45/00; A61P25/00; A61P25/14; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; C07D243/10; C07D243/38; C07D267/18; C07D281/10; C07D401/04; C07D403/04; C07D471/04; C07D487/08; C07D513/04
Domestic Patent References:
| JPS4913189A | 1974-02-05 |
Foreign References:
| FR1334944A | 1963-08-16 | |||
| CH422793A | 1966-10-31 | |||
| CH476753A | 1969-08-15 |
Attorney, Agent or Firm:
Koichi Kajisaki
Yuzo Ozaki
Toshihiko Taniguchi
Yuzo Ozaki
Toshihiko Taniguchi