Title:
治療剤としてのアミノアダマンタン誘導体
Document Type and Number:
Japanese Patent JP4317343
Kind Code:
B2
Abstract:
The present invention provides novel aminoadamantane derivatives, methods of making the derivatives, compositions including the novel aminoadamantane derivatives, and methods for the treatment and prevention of neurological diseases using the derivatives and compositions. There are a variety of neurological disorders that can be treated using the present invention, including, for example, the following: neurological disorders arising from trauma, ischemic or hypoxic conditions that can be treated include stroke, hypoglycemia, cerebral ischemia, cardiac arrest, spinal cord trauma, head trauma, perinatal hypoxia, cardiac arrest and hypoglycemic neuronal damage; neurodegenerative disorders such as epilepsy, Alzheimer's disease, Huntington's disease Parkinsonism, and amyotrophic lateral sclerosis; other diseases or disorders such as convulsion, pain, depression, anxiety, schizophrenia, muscle spasms, migraine headaches, urinary incontinence, nicotine withdrawal, opiate tolerance and withdrawal, emesis, brain edema, tardive dyskinesia, AIDS-induced dementia, ocular damage, retinopathy, cognitive disorders, and neuronal injury associated with HIV-infection such as dysfunction in cognition, movement and sensation.
Inventors:
One, utian
Ye, Wenchin
Larrick, James W.
Stanler, Jonathan S.
Lipton, Stuart A.
Ye, Wenchin
Larrick, James W.
Stanler, Jonathan S.
Lipton, Stuart A.
Application Number:
JP2001561716A
Publication Date:
August 19, 2009
Filing Date:
February 22, 2001
Export Citation:
Assignee:
Panorama Research, Incorporated
International Classes:
A61P1/08; A61K31/133; C07C211/38; A61K31/135; A61K31/164; A61K31/196; A61K31/21; A61K31/221; A61K31/27; A61P9/02; A61P9/04; A61P9/10; A61P13/10; A61P17/02; A61P21/00; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/22; A61P25/28; A61P25/34; A61P25/36; A61P27/02; C07C209/76; C07C213/00; C07C215/44; C07C219/24; C07C231/12; C07C233/23; C07C233/52; C07C269/06; C07C271/24
Domestic Patent References:
| JP11106360A | ||||
| JP2002531547A |
Foreign References:
| GB1173492A |
Other References:
Chemical & Pharmaceutical Bulletin,1985年,Vol.33 No.11,p.4680-4684
Journal of Organic Chemistry,1996年,Vol.61 No.4,p.1413-1422
Journal of the American Chemical Society,1973年,Vol.95 No.26,p.8631-8637
Fresenius' Zeitschrift fuer Analytische Chemie,1985年,Vol.321 No.4,p.363-370
Zhurnal Organicheskoi Khimii,1984年,Vol.20 No.7-8,p.1435-1438
European Journal of Organic Chemistry,2000年,No.19,p.3357-3362
Journal of Organic Chemistry,1996年,Vol.61 No.4,p.1413-1422
Journal of the American Chemical Society,1973年,Vol.95 No.26,p.8631-8637
Fresenius' Zeitschrift fuer Analytische Chemie,1985年,Vol.321 No.4,p.363-370
Zhurnal Organicheskoi Khimii,1984年,Vol.20 No.7-8,p.1435-1438
European Journal of Organic Chemistry,2000年,No.19,p.3357-3362
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
Previous Patent: 高変換された二酸化塩素の溶液を製造するための重量物体
Next Patent: MANUFACTURING APPARATUS FOR SEMICONDUCTOR DEVICE
Next Patent: MANUFACTURING APPARATUS FOR SEMICONDUCTOR DEVICE