Title:
アミノアルキルフェノール、その使用及び製造方法
Document Type and Number:
Japanese Patent JP5062954
Kind Code:
B2
Abstract:
The present invention relates to Mannich base antimalarial aminoalkylphenol compounds and their use against protozoa of the genus Plasmodium, particularly emerging strains of drug-resistant Plasmodia. This invention further relates to compositions containing such compounds and a process for making the compounds. This and other aspects of the invention are realized upon review of the entire specification.
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Inventors:
Dorn, Conrad P
Paulus, Mary Ann
Walshille, Thomas F
Weibrato, Machine Jay
Paulus, Mary Ann
Walshille, Thomas F
Weibrato, Machine Jay
Application Number:
JP2004515965A
Publication Date:
October 31, 2012
Filing Date:
June 20, 2003
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07C215/46; C07D249/08; A01N33/02; A61K31/122; A61K31/135; A61K31/137; A61K31/155; A61K31/341; A61K31/35; A61K31/357; A61K31/381; A61K31/4196; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/4706; A61K31/49; A61K31/505; A61K31/635; A61P33/06; C07C215/28; C07C215/50; C07C215/52; C07C215/54; C07C217/58; C07C229/14; C07C233/18; C07D213/36; C07D295/08; C07D307/28; C07D309/04; C07D319/12; C07D333/48
Foreign References:
| US3794734 |
Other References:
Journal of Medicinal Chemistry,1980年,Vol.23,p.1414-1427
Journal of Medicinal Chemistry,1969年,Vol.12,p.711-712
Journal of the American Chemical Society,1946年,Vol.68,p.1894-1901
Journal of Medicinal Chemistry,1969年,Vol.12,p.711-712
Journal of the American Chemical Society,1946年,Vol.68,p.1894-1901
Attorney, Agent or Firm:
Yoshio Kawaguchi
Katsuma Osaki
Katsuma Osaki