Title:
B-ホモアンドロスタンおよびB-ヘテロアンドロスタンのアミノ誘導体
Document Type and Number:
Japanese Patent JP4664433
Kind Code:
B2
Abstract:
New aminoalkoxyimino derivatives at position 3 of substituted B-homoandrostanes and B-heteroandrostanes, processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, such as heart failure and hypertension. In particular compounds having the general formula (I) are described, where the radicals have the meanings described in detail in the application.
Inventors:
Alberto Celli
Barbara Morro
Mako Torri
Julio Calzana
Giuseppe Bianchi
Marla Ferrandy
Patrizia Ferrari
Maria Pier Zappavigna
Leonardo Banffy
Giuseppe Jacarone
Barbara Morro
Mako Torri
Julio Calzana
Giuseppe Bianchi
Marla Ferrandy
Patrizia Ferrari
Maria Pier Zappavigna
Leonardo Banffy
Giuseppe Jacarone
Application Number:
JP2009517074A
Publication Date:
April 06, 2011
Filing Date:
May 31, 2007
Export Citation:
Assignee:
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SOCIETA PER AZIONI
International Classes:
C07J63/00; A61K31/5685; A61K31/58; A61P9/00; A61P9/02; A61P9/04; A61P9/12; A61P13/12; C07J73/00
Foreign References:
| EP0825197A1 | ||||
| WO2006002381A1 | ||||
| US3328408 |
Other References:
MUNARI DE S,JOURNAL OF MEDICINAL CHEMISTRY,米国,AMERICAN CHEMICAL SOCIETY,2003年 7月23日,V46 N17,P3644-3654
STARKA, L.,SBORNIK LEKARSKY,1997年,V98 N1
RAZDAN R K,JOURNAL OF MEDICINAL CHEMISTRY,1976年 5月,V19 N5,P719-721
STARKA, L.,SBORNIK LEKARSKY,1997年,V98 N1
RAZDAN R K,JOURNAL OF MEDICINAL CHEMISTRY,1976年 5月,V19 N5,P719-721
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga