Title:
AMINOALCOHOL DERIVATIVES AND PREPARATION THEREOF
Document Type and Number:
Japanese Patent JPS5297952
Kind Code:
A
Abstract:
Aminoalcohol derivatives corresponding to the formula (I) in which Q is a group and the other substituents have the meaning shown in Claim 1 are prepared by reaction with a compound of formula I, in which Q represents a group or , with an amine of type R3R4NH, Z being a halogen. The alcohol can then be esterified by reaction with an acid or an anhydride as defined in Claim 1. The compounds obtained have activities on the cardiovascular system, for example antihypertensive and/or antispasmodic activities, peripheral vasodilative activity, protective activity against myocardial anoxia, hypolipidemiating activity, antithrombotic activity, beta -lytic activity or platelet aggregation inhibiting activity, and/or activity on the central nervous system, for example a tranquillising activity.
Inventors:
JIYORUJIYU RANBERIN
YOZEFU ROOBA
KUROODO GIRE
ROMEO RONKUSHI
YOZEFU ROOBA
KUROODO GIRE
ROMEO RONKUSHI
Application Number:
JP13785976A
Publication Date:
August 17, 1977
Filing Date:
November 18, 1976
Export Citation:
Assignee:
CONTINENTAL PHARMA
International Classes:
A61K31/135; A61K31/195; A61K31/215; A61K31/22; A61K31/335; A61K31/38; A61K31/381; A61K31/382; A61K31/395; A61K31/435; A61K31/495; A61K31/535; A61K31/54; A61P3/06; A61P9/00; A61P9/08; A61P9/12; A61P25/26; B01J23/00; B01J25/00; B01J27/00; B01J31/00; C07B61/00; C07C67/00; C07C213/00; C07C215/38; C07C217/56; C07C219/22; C07C225/16; C07C233/43; A61K31/13; C07C233/73; C07C233/78; C07C255/24; C07C255/30; C07C255/58; C07C271/16; C07C311/01; C07C313/00; C07C323/25; C07C323/27; C07C323/32; C07C323/33; C07C323/41; C07C323/49; C07C323/62; C07D209/08; C07D211/14; C07D215/06; C07D223/16; C07D265/30; C07D265/36; C07D277/60; C07D279/08; C07D281/10; C07D307/79; C07D311/04; C07D313/08; C07D327/00; C07D327/06; C07D333/54; C07D335/06; C07D337/06; C07D337/08; C07D339/00; C07D339/06; C07D339/08; C07D401/10; C07D401/12; C07D403/10; C07D405/06; C07D409/06; C07D409/12; (IPC1-7): C07C91/14; C07D333/54; C07D335/06; C07D409/06; C07D211/08; C07D337/06; C07D223/30; C07D409/12; C07D295/02