アルツハイマー病の治療に有用なアミノジオール

Japanese Patent JP2005519874

A

The present invention relates to the treatment of Alzheimer's disease and other similar diseases, and more specifically to the use of compounds that inhibit beta-secretase, an enzyme that cleaves amyloid precursor protein to produce A beta peptide, a major component of the amyloid plaques found in the brains of Alzheimer's sufferers, in such methods.

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Show Starlets, Heinrich, Jay.
Hanson, Gunnar, Jay.

JP2003545299A

July 07, 2005

November 19, 2002

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Pharmacia and Upjohn
PHARMACIA & UPJOHN COMPANY

A61K31/00; A61K31/13; A61K31/165; A61K31/18; A61K31/216; A61K31/27; A61K31/341; A61K31/353; A61K31/397; A61K31/4035; A61K31/404; A61K31/4172; A61K31/4184; A61K31/426; A61K31/439; A61K31/4402; A61K31/4409; A61K31/445; A61K31/4453; A61K31/46; A61K31/472; A61K31/495; A61K31/5375; A61K31/5386; A61K31/54; A61K31/553; A61P25/28; A61P43/00; C07D209/42; C07D209/44; C07D211/14; C07D211/38; C07D211/40; C07D211/78; C07D213/40; C07D213/42; C07D215/12; C07D215/18; C07D217/04; C07D217/14; C07D221/26; C07D233/61; C07D233/64; C07D235/06; C07D265/10; C07D267/10; C07D277/20; C07D277/30; C07D295/10; C07D295/12; C07D307/84; C07D311/24; C07D487/08; C07D498/18; C07D295/04; (IPC1-7): A61K31/165; A61K31/18; A61K31/216; A61K31/27; A61K31/341; A61K31/353; A61K31/397; A61K31/4035; A61K31/404; A61K31/4172; A61K31/4184; A61K31/426; A61K31/439; A61K31/4402; A61K31/4409; A61K31/445; A61K31/4453; A61K31/46; A61K31/472; A61K31/495; A61K31/5375; A61K31/5386; A61K31/54; A61K31/553; A61P25/28; A61P43/00

Hideto Asamura
Hajime Asamura
Katsunori Ando
Makoto Koike

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