Title:
AMINOPROPANE DERIVATIVE
Document Type and Number:
Japanese Patent JPS56139448
Kind Code:
A
Abstract:
The invention relates to a compound of the formula wherein R1 is a linear or branched alkyl of 4 to 20 carbon atoms; R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms or a bivalent radical -CH=CH-CH=CH- or -(CH2)n-, where n is an integer from 3 to 5, inclusive, and the free bonds of said bivalent radical are attached to adjacent carbon atoms of the phenyl ring; and R3 is hydrogen or alkyl of 1 to 3 carbon atoms; R4 is alkyl of 1 to 3 carbon atoms; or R3 and R4, together with each other, are -(CH2)p-, where p is an integer from 4 to 6, inclusive, or a non-toxic, pharmacologically acceptable acid addition salt thereof. The compounds of formula I are useful for treatment and prophylaxis of diseases of the coronaries, for the treatment of hypertension, and for treatment of cardiac arrhythmia, particularly tachycardia.
Inventors:
HERUBERUTO KOTSUPE
BERUNAA KUMAA
HERUMUTSUTO SUTAARE
GOYUKO MUASEBITSUKU
BERUNAA TORAUNETSUKAA
BERUNAA KUMAA
HERUMUTSUTO SUTAARE
GOYUKO MUASEBITSUKU
BERUNAA TORAUNETSUKAA
Application Number:
JP3236681A
Publication Date:
October 30, 1981
Filing Date:
March 06, 1981
Export Citation:
Assignee:
BOEHRINGER SOHN INGELHEIM
International Classes:
A61K31/275; A61K31/505; A61P9/00; C07C67/00; C07C253/00; C07C255/59; C07C255/60; (IPC1-7): A61K31/275; C07C120/00; C07C121/80
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