Title:
Aniline derivatives, those manufacture, and those medical treatment application
Document Type and Number:
Japanese Patent JP6272976
Kind Code:
B2
Abstract:
The present invention relates to therapeutic applications of aniline derivatives of formula (I), for example in treating glaucoma: Formula (I), R1a represents H, an halogen, a (C1-C6)alkyl or a CN; R1b represents H, an halogen or a (C1-C6)alkyl; R1c represents H or a (C1-C6)alkyl; R2 represents H, an halogen, an OH, an O—(C1-C6)alkyl or (C1-C6)alkyl; R3 represents H, an halogen, a (C1-C6)alkyl, an OH, an O—(C1-C6)alkyl, a CONH2 or CN; R4 represents H, an halogen or a (C1-C6)alkyl; R5 represents H or F: R7 represents H or F; R8 represents H or F; R9 represents H or (C1-C6)alkyl, or one of its enantiomers.
Inventors:
Futril, John
Le Riche, Caroline
Middle miss, david
Le Riche, Caroline
Middle miss, david
Application Number:
JP2016215821A
Publication Date:
January 31, 2018
Filing Date:
November 04, 2016
Export Citation:
Assignee:
SANOFI
International Classes:
C07C217/84; A61K31/165; A61K31/196; A61K31/216; A61K31/5375; A61P27/06; C07C213/06; C07C213/08; C07C231/12; C07C235/06; C07C253/30; C07C255/59; C07D295/088
Domestic Patent References:
| JP2011510965A | ||||
| JP2009505973A | ||||
| JP2007230993A |
Foreign References:
| WO2010111449A1 | ||||
| WO2005080367A1 | ||||
| WO2005087710A1 |
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi