Title:
HIV誘発疾患の動物モデル
Document Type and Number:
Japanese Patent JP2009525054
Kind Code:
A
Abstract:
HIV does not cause disease in any non-human species. Thus, there is no animal model system to evaluate the efficacy of strategies aimed at preventing, treating or curing disease caused by this virus. The present invention provides compositions and a method for producing an animal model for HIV induced disease. The present invention is an animal adapted to simulate a human-like immune response to HIV, which is accomplished by activation and inactivation of complement of proteins within the animal. Accordingly, the present invention stages certain human proteins within an animal by way of its gut associated lymphoid tissue followed by infection of live HIV.
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Inventors:
Nelson M. Carp
Application Number:
JP2008553412A
Publication Date:
July 09, 2009
Filing Date:
February 05, 2007
Export Citation:
Assignee:
Nelson M. Carp
International Classes:
A01K67/027; C07K14/155; C12N7/00; C12N15/09
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro