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Title:
Annular Urea or a lactam substitution quinoxaline type piperidine compound, and its use
Document Type and Number:
Japanese Patent JP6173453
Kind Code:
B2
Abstract:
The disclosure relates to Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein R1, R2, Qa, Y1, Z, A, B, Qx, E, G, J, M, U, W, and a are as defined herein, compositions comprising an effective amount of a Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compound.

Inventors:
Tatsuhiko Ueno
Maki Tsuno
Shu, Xiao Ming
Application Number:
JP2015524857A
Publication Date:
August 02, 2017
Filing Date:
July 29, 2013
Export Citation:
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Assignee:
PURDUE PHARMA L.P.
Shionogi Pharmaceutical Co., Ltd.
International Classes:
C07D451/04; A61K31/498; A61K31/513; A61K31/53; A61K31/5386; A61P1/10; A61P1/12; A61P1/14; A61P3/04; A61P7/12; A61P9/12; A61P11/14; A61P25/04; A61P25/08; A61P25/16; A61P25/22; A61P25/24; A61P25/28; A61P25/36; A61P43/00; C07D451/14; C07D498/08
Domestic Patent References:
JP2010537969A
JP2002522431A
Foreign References:
WO2012085648A1
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki