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Title:
アンサマイシン製剤およびその使用法
Document Type and Number:
Japanese Patent JP2010512397
Kind Code:
A
Abstract:
Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 (Hsp90).

Inventors:
Austad, Bryan Sea.
Grenier, Lewis
Holson, Edward Bee.
Lee, John Jay.
Park, Roger H.
Porter, James Earl.
Wright, James L.
Application Number:
JP2009541348A
Publication Date:
April 22, 2010
Filing Date:
December 11, 2007
Export Citation:
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Assignee:
INFINITY DISCOVERY, INC.
International Classes:
A61K31/395; A61K47/10; A61K47/14; A61K47/20; A61K47/26; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/40; A61K47/42; A61P35/00; A61P35/02; C07D225/06
Domestic Patent References:
JPH08506356A1996-07-09
JP2005504086A2005-02-10
Foreign References:
WO2007002093A22007-01-04
WO2006050457A22006-05-11
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita