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Title:
ANTHRAPYRAZOLE COMPOUND AND AN ANTITUMOR AGENT CONTAINING THE SAME
Document Type and Number:
Japanese Patent JPH07165726
Kind Code:
A
Abstract:

PURPOSE: To obtain a new anthrapyrazole compound useful as an antitumor agent having excellent antitumor activity and low toxicity.

CONSTITUTION: A compound of the formula [R1 and R2 are each H, OH, an alkyl, a hydroxyalkyl, an alkoxyalkyl, an alkenyl, a hydroxyalkenyl, an alkoxyalkenyl or an acyl (with the proviso that a case wherein both R1 and R2 are H or OH at the same time or one of R1 and R2 is H and the other is OH is omitted); R3 and R4 are each an alkyl, a hydroxyalkyl, an alkoxyalkyl, (CH2)n-NR5R6 (R5 and R6 are each H, an alkyl, a hydroxyalkyl, an alkoxyalkyl, an aminoalkyl or a primary or a secondary alkylaminoalkyl; (n) is 1-6)] such as 10-ethyl-7-hydroxy-2-[(2-hydroxyethyl)amino]ethyl]-5-methylaminoanthra[1,9- cd]pyrazoto-6(2H)-one.


Inventors:
HONDA TADASHI
YUNOU TAKEO
ITO YUKIYASU
MANABE SHUNICHI
Application Number:
JP30818893A
Publication Date:
June 27, 1995
Filing Date:
December 08, 1993
Export Citation:
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Assignee:
JAPAN TOBACCO INC
International Classes:
C07D231/54; A61K31/415; A61P35/00; C07C50/24; C07F7/18; (IPC1-7): C07D231/54; A61K31/415; C07C50/24; C07F7/18