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Title:
抗TIGIT抗体
Document Type and Number:
Japanese Patent JP6920194
Kind Code:
B2
Abstract:
The present invention relates to anti-TIGIT antibodies, as well as use of these antibodies in the treatment of diseases such as cancer and infectious disease.

Inventors:
Williams, Civil M. G.
Face, drake
Fayadat-Dillman, Lawrence
Laguna Tan, Goparan
Lian, Linda
Segetzi, Wolfgang
Application Number:
JP2017509009A
Publication Date:
August 18, 2021
Filing Date:
August 17, 2015
Export Citation:
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Assignee:
Merck Sharp & Dohme Corp.
International Classes:
C12N15/13; A61K47/42; A61K47/68; A61P31/00; A61P35/00; A61P37/04; A61P43/00; C07K16/28; C07K16/46; C12N1/19; C12N5/10; C12P21/08; G01N33/53
Domestic Patent References:
JP2010517538A
JP2013531970A
Other References:
Proc.Natl.Acad.Sci.USA,2009年,Vol.106,NO.42,p.17858-17863
Nat.Immunol.,2009年,Vol.10,p.48-57
J.Immunol.,2013年,Vol.190,p.4899-4899
Cancer Cell,2014年,Vol.26,p.923-937
Attorney, Agent or Firm:
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yoshikazu Iwase
Yasufumi Shiroyama