Title:
抗-凝固性のペプチジル‐アルギニンアルデヒド誘導体
Document Type and Number:
Japanese Patent JP3970935
Kind Code:
B2
Abstract:
The invention relates to new peptidyl-arginine aldehyde compounds of formula (I)whereinQ represents an acyl group of formula Q'-OCO, wherein Q' represents an alkyl-group with 1-3 carbon atoms,D-Xaa represents a 3-cyclobutyl-D-alanyl- or 3-cyclopentyl-D-alanyl group,Pro represents an L-prolyl group, andArg represents an L-arginyl group,and acid-addition salts thereof, and pharmaceutical compositions comprising them, which are suitable for the prevention and cure of thrombosis and accelerated blood clotting.
Inventors:
Bayus, Shandol
Juhas, Attila
Barabas, Eva
Feher, Andras
Sabo, Cabriera
Sale, Erjebeto
Wakehe Yui, Elaine
Lavitz, Emilia
Cassar, Eva
Rango, Josef
Moravchik, Imre
Sequel, Argnes
Tashturel, Giuzanna
Tote, garbol
Mojai, Giuzanna
Anna Kai, Salkai
Mac, clara
Juhas, Attila
Barabas, Eva
Feher, Andras
Sabo, Cabriera
Sale, Erjebeto
Wakehe Yui, Elaine
Lavitz, Emilia
Cassar, Eva
Rango, Josef
Moravchik, Imre
Sequel, Argnes
Tashturel, Giuzanna
Tote, garbol
Mojai, Giuzanna
Anna Kai, Salkai
Mac, clara
Application Number:
JP50035298A
Publication Date:
September 05, 2007
Filing Date:
June 05, 1997
Export Citation:
Assignee:
IVAX DRUG RESEARSH INSTITUTE LTD.
International Classes:
C07K5/06; A61K31/00; A61K38/00
Domestic Patent References:
| JP4257600A | ||||
| JP5112598A | ||||
| JP61152699A |
Attorney, Agent or Firm:
Soichi Takezawa
Yutaka Kuramochi
Yutaka Kuramochi