Title:
抗炎症剤及びその使用
Document Type and Number:
Japanese Patent JP6713687
Kind Code:
B2
Abstract:
An anti-inflammatory drug containing a G0/G1 switch 2 (G0S2) inhibitor as an active ingredient is useful as a novel anti-inflammatory drug.
Inventors:
Shigehiro Oto
Naoya Matsunaga
Akio Ojida
Naoya Shindo
Naoya Matsunaga
Akio Ojida
Naoya Shindo
Application Number:
JP2016572138A
Publication Date:
July 01, 2020
Filing Date:
January 28, 2016
Export Citation:
Assignee:
Kyushu University
International Classes:
A61K31/155; A61K31/27; A61P29/00; C07C279/04; C07C279/14; C07D249/04; C12Q1/32; G01N33/15; G01N33/50
Domestic Patent References:
| JP2014530813A | ||||
| JP6506455A | ||||
| JP9255589A | ||||
| JP2000515895A |
Foreign References:
| WO1999002145A1 | ||||
| FR2147881A1 | ||||
| US3109859 |
Other References:
Cristillo, A.D. et al., Cyclosporin A inhibits early mRNA expression of G0/G1 switch gene 2 (G0S2) i
田中千賀子他編,「NEW 薬理学」,株式会社南江堂,1997,p.467-9
Xin Lu et al, NF-κB increased expression of 17β-hydroxysteroid dehydrogenase 4 promotes HepG2 prol
Chen, Chun-Yen et al., One-flask' transformation of isocyanates and isothiocyanates to guanidines hy
Boguszewski, Paul A. et al., Modular Three-Component Solid-Phase Synthesis of Unsymmetrical Guanidin
Goessnitzer, Edith et al., Novel high energy intermediate analogues with a triazasterol structure as
Goessnitzer, Edith et al., Novel high energy intermediate analogs with triazasterol-related structur
McKay, A. F. et al., Bacteriostats. VI. Bacteriostatic activities of some substituted guanidines, Jo
Neidlein, Richard et al., N-Acylcarbodiimides, Archiv der Pharmazie, 1966, vol.299, no.8, p.709-14,
O'Donovan, Daniel H. et al., Tetrahedron Letters, A concise synthesis of asymmetrical N,N'-disubstit
Ma, Dawei et al., Aromatic Nucleophilic Substitution or CuI-Catalyzed Coupling Route to Martinellic
Linton, Brian R. et al., A Versatile One-Pot Synthesis of 1,3-Substituted Guanidines from Carbamoyl
田中千賀子他編,「NEW 薬理学」,株式会社南江堂,1997,p.467-9
Xin Lu et al, NF-κB increased expression of 17β-hydroxysteroid dehydrogenase 4 promotes HepG2 prol
Chen, Chun-Yen et al., One-flask' transformation of isocyanates and isothiocyanates to guanidines hy
Boguszewski, Paul A. et al., Modular Three-Component Solid-Phase Synthesis of Unsymmetrical Guanidin
Goessnitzer, Edith et al., Novel high energy intermediate analogues with a triazasterol structure as
Goessnitzer, Edith et al., Novel high energy intermediate analogs with triazasterol-related structur
McKay, A. F. et al., Bacteriostats. VI. Bacteriostatic activities of some substituted guanidines, Jo
Neidlein, Richard et al., N-Acylcarbodiimides, Archiv der Pharmazie, 1966, vol.299, no.8, p.709-14,
O'Donovan, Daniel H. et al., Tetrahedron Letters, A concise synthesis of asymmetrical N,N'-disubstit
Ma, Dawei et al., Aromatic Nucleophilic Substitution or CuI-Catalyzed Coupling Route to Martinellic
Linton, Brian R. et al., A Versatile One-Pot Synthesis of 1,3-Substituted Guanidines from Carbamoyl
Attorney, Agent or Firm:
Sumio Tanai
Yasushi Matsunuma
Shu Oikawa
Masato Iida
Yasushi Matsunuma
Shu Oikawa
Masato Iida