Title:
ANTI-INFLAMMATORY COMPOUND
Document Type and Number:
Japanese Patent JP2015174850
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide an anti-inflammatory drug and an anti-inflammatory cytokine inhibitor including a new phospholipid having a high anti-inflammatory action and a specified acidic lipid.SOLUTION: Provided is an anti-inflammatory drug or an inflammatory cytokine production inhibitor including 1-eicosapentaenoyl-2-(3-hydroxy)palmitoylphosphatidyl glycerol and a lipid as fatty acid in which the number of carbons is 20 or higher and the number of double bonds is 4 or more, being a glycero type acidic substance in which two fatty acids are coupled to the 1, 2 positions of a glycerol skeleton.
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Inventors:
TSUGE KEISUKE
YOSHIMURA TAKASHI
TSURUTA HIROMI
YOSHIMURA TAKASHI
TSURUTA HIROMI
Application Number:
JP2014053518A
Publication Date:
October 05, 2015
Filing Date:
March 17, 2014
Export Citation:
Assignee:
SAGA PREFECTURE
International Classes:
C07F9/10; A23L1/30; A61K8/55; A61K8/97; A61K31/683; A61K36/02; A61K36/05; A61P29/00; A61Q19/00
Domestic Patent References:
| JP2001172130A | 2001-06-26 | |||
| JP2011206016A | 2011-10-20 | |||
| JP2006232766A | 2006-09-07 | |||
| JPH09173012A | 1997-07-08 |
Foreign References:
| KR20130117491A | 2013-10-28 |
Other References:
BANSKOTA, ARJUN H. ET AL.,: "Polar lipids from the marine macroalga Palmaria palmata inhibit lipopolysaccharide-induced nitric ox", PHYTOCHEMISTRY, vol. (2014), 101, 101-108, JPN6018000193, 2014, ISSN: 0003898492
MORGAN, ALWENA H. ET AL.,: "Phosphatidylethanolamine-esterified Eicosanoids in the Mouse: TISSUE LOCALIZATION AND INFLAMMATION-D", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. (2009), 284(32), 21185-21191, JPN7018000007, 2009, ISSN: 0003898493
BANSKOTA, ARJUN H. ET AL.,: "New diacylglyceryltrimethylhomoserines from the marine microalga Nannochloropsis granulata and their", JOURNAL OF APPLIED PHYCOLOGY, vol. (2013), 25(5), 1513-1521, JPN6018014111, 2013, ISSN: 0003781066
MORGAN, ALWENA H. ET AL.,: "Phosphatidylethanolamine-esterified Eicosanoids in the Mouse: TISSUE LOCALIZATION AND INFLAMMATION-D", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. (2009), 284(32), 21185-21191, JPN7018000007, 2009, ISSN: 0003898493
BANSKOTA, ARJUN H. ET AL.,: "New diacylglyceryltrimethylhomoserines from the marine microalga Nannochloropsis granulata and their", JOURNAL OF APPLIED PHYCOLOGY, vol. (2013), 25(5), 1513-1521, JPN6018014111, 2013, ISSN: 0003781066
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office