Title:
【発明の名称】部分的なアゴニスト活性を有している抗プロゲスチン
Document Type and Number:
Japanese Patent JP2003528137
Kind Code:
A
Abstract:
The present invention features methods of inhibiting progestin activity in a cell or in a subject in need of such inhibition, and methods of treating or preventing progestin-dependent conditions in a subject in need of such treatment or prevention. The methods include administering an effective amount of a C-17-derivatized dexamethasone antiprogestin to the cell or the subject. The invention also provides methods of screening substances for progestin or antiprogestin activity, and methods of detecting progestins, progestin agonists, or antiprogestins in a sample, using the C-17-derivatized dexamethasone antiprogestins of the invention.
Inventors:
Simon's, S. Stoney Jr.
Application Number:
JP2001570254A
Publication Date:
September 24, 2003
Filing Date:
March 23, 2001
Export Citation:
Assignee:
The Government of the United States of America, As Represented by the Secretary, Department of Health and Human Services
International Classes:
G01N33/53; A61K31/573; A61K31/585; A61P5/32; A61P7/06; A61P15/00; A61P15/04; A61P15/08; A61P15/18; A61P35/00; C07J5/00; C07J21/00; C12Q1/68; G01N33/74; (IPC1-7): A61K31/573; A61K31/585; A61P5/32; A61P7/06; A61P15/00; A61P15/04; A61P15/08; A61P15/18; A61P35/00; C07J5/00; C07J21/00; C12Q1/68; G01N33/53
Attorney, Agent or Firm:
Shusaku Yamamoto (2 outside)