ANTI-RANTES ANTIBODIES AND METHODS OF USE THEREOF

Title:

ANTI-RANTES ANTIBODIES AND METHODS OF USE THEREOF

Document Type and Number:

Japanese Patent JP2013234204

Kind Code:

A

Abstract:

To provide anti-rantes antibodies and to provide methods of use thereof.

The invention relates to fully human monoclonal antibodies, and fragments thereof, that bind to the chemokine Regulated upon Activation, Normal T-cell Expressed, and Secreted (RANTES, CCL5), thereby modulating the interaction between RANTES and one or more of its receptors, such as, e.g., CCR1, CCR3, CCR4 and CCR5, and/or modulating the biological activities of RANTES. The invention also relates to the use of these or optional anti-RANTES antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.

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Inventors:

FISCHER NICOLAS
KOSCO-VILBOIS MARIE
MACH FRANCOIS

Application Number:

JP2013174442A

Publication Date:

November 21, 2013

Filing Date:

August 26, 2013

Export Citation:

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Assignee:

NOVIMMUNE SA

International Classes:

C07K16/18; A61K39/395; A61K45/00; A61P1/04; A61P1/10; A61P1/12; A61P1/14; A61P7/06; A61P9/08; A61P9/10; A61P11/00; A61P17/06; A61P19/02; A61P29/00; A61P37/02; C12N15/09

Attorney, Agent or Firm:

Hidesaku Yamamoto
Natsuki Morishita

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