Title:
抗ＲＯＲ１抗体とその作製及び使用方法
Document Type and Number:
Japanese Patent JP7222987
Kind Code:
B2
Abstract:
The application provides anti-ROR1 monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.
Inventors:
Olsen, Ole
Tan, Phil
Shea, Don
Jerryman, David
Kovacevich, Bryan
brady, bill
Renshaw, Blair
Gao, Zelen
two, i
Tan, Phil
Shea, Don
Jerryman, David
Kovacevich, Bryan
brady, bill
Renshaw, Blair
Gao, Zelen
two, i
Application Number:
JP2020520426A
Publication Date:
February 15, 2023
Filing Date:
June 22, 2018
Export Citation:
Assignee:
SYSTIMMUNE, INC.
International Classes:
C12N15/13; A61K31/704; A61K39/395; A61K45/00; A61K47/68; A61P35/02; A61P37/04; A61P43/00; C07K16/30; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; C12P21/08
Domestic Patent References:
| JP2015532644A |
Foreign References:
| WO2012076066A2 | ||||
| US20130251642 |
Other References:
Clin. Cancer Res.,2017年06月15日,Vol.23, No.12,pp.3061-3071
Attorney, Agent or Firm:
SK Patent Attorney Corporation
Akihiko Okuno
Hiroyuki Ito
Akihiko Okuno
Hiroyuki Ito