ANTI-TUMOR SUBSTANCE, BE-41926 - BANYU PHARMA CO LTD

Title:

ANTI-TUMOR SUBSTANCE, BE-41926

Document Type and Number:

Japanese Patent JPH10168054

Kind Code:

A

Abstract:

To obtain the subject new substance with excellent anti-tumor action, useful in the medical and pharmaceutical fields by innoculating a BE-41926 producing bacterium strain in a medium containing nutritional sources and culturing it aerobically.

This substance, BE-41926, of the formula, is obtained by culturing microorganisms belonging to the genus Streptomyces sp. A41926 (FERM P-15780). As for nutritional sources, glucose or sugar is used as a carbon source and soybean meal or fish meal is used as a nitrogen source. The bacteria are cultured according to the same method as general methods for producing metabolites from bacteria at a culturing temperature of suitably 12-39°C, preferably, 21-28°C at a pH range of 4-8 for 48-240hrs, preferably, 72-192hrs. The objective BE-41926 is collected from the cultured product according to conventional separating means.

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Inventors:

NISHIOKA HIROSHI
NAKASE KAZUHO
NAKAJIMA SHIGERU
NAGASHIMA MASAO
OJIRI KATSUHISA
SUDA HIROYUKI

Application Number:

JP35186696A

Publication Date:

June 23, 1998

Filing Date:

December 11, 1996

Export Citation:

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Assignee:

BANYU PHARMA CO LTD

International Classes:

C12P11/00; C07C323/22; C12R1/465; (IPC1-7): C07C323/22; C12P11/00

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